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Article

Protein kinase A phosphorylates NCoR to enhance its nuclear translocation and repressive function in human prostate cancer cells.

Journal of cellular physiology - 1 Jun 2013

Choi Hyo-Kyoung, Yoo Jung-Yoon, Jeong Mi-Hyeon, Park Soo-Yeon, Shin Dong-Myoung, Jang Sung-Wuk, Yoon Ho-Geun, Choi Kyung-Chul

Abstract excerpt

Protein kinase A (PKA) phosphorylates diverse protein substrates to modulate their function. In this study, we found that PKA specifically phosphorylates the RD1 (repression domain 1) domain of nuclear receptor corepressor (NCoR). We demonstrated that the Serine-70 of NCoR is identified the criti...

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Identifiers

PMID: 23129261
DOI: 10.1002/jcp.24269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23129261-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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