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Article

Post-Translational Modifications of Nuclear Receptors and Human Disease

1 Jan 2012

Abstract excerpt

Nuclear receptors (NR) impact a myriad of physiological processes including homeostasis, reproduction, development, and metabolism. NRs are regulated by post-translational modifications (PTM) that markedly impact receptor function. Recent studies have identified NR PTMs that are involved in the onset and progression of human diseases, including cancer. The majority of evidence linking NR PTMs with disease has...

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PMID: 22438791
DOI: 10.1621/nrs.10001

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