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Some Basic Aspects of HLA-G Biology

1 Jan 2014

Abstract excerpt

Human leukocyte antigen-G (HLA-G) is a low polymorphic nonclassical HLA-I molecule restrictively expressed and with suppressive functions. HLA-G gene products are quite complex, with seven HLA-G isoforms, four membrane bound, and other three soluble isoforms that can suffer different posttranslational modifications or even complex formations. In addition, HLA-G has been described included in exosomes. In this...

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PMID: 24818168
DOI: 10.1155/2014/657625

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