Article
Haptoglobin (HP) polymorphisms and human longevity: a cross-sectional association study in a Central Italy population.
Clinica chimica acta; international journal of clinical chemistry - 18 Mar 2011
Napolioni Valerio, Giannì Paola, Carpi Francesco M, Concetti Fabio, Lucarini Nazzareno
Abstract excerpt
BACKGROUND: Haptoglobin (HP), which scavenges free, cell-toxic hemoglobin and has anti-inflammatory and immune-modulatory function in extravascular tissues, may represent an excellent candidate gene to investigate the life-span expectancy. METHODS: HP 1/2 polymorphism has been determined for 1072 (569 females, 503 males) unrelated healthy individuals from Central Italy, 18-106 years old, divided into three...
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