Article
Sex and age specificity of susceptibility genes modulating survival at old age.
Human heredity - 1 Jan 2006
Passarino Giuseppe, Montesanto Alberto, Dato Serena, Giordano Sabrina, Domma Filippo, Mari Vincenzo, Feraco Emidio, De Benedictis Giovanna
Abstract excerpt
OBJECTIVE: We aimed to investigate the influence of the genetic variability of candidate genes on survival at old age in good health. METHODS: First, on the basis of a synthetic survival curve constructed using historic mortality data taken from the Italian population from 1890 onward, we defined three age classes ranging from 18 to 106 years. Second, we assembled a multinomial logistic regression model to...
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