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Article

H(1)R expression by CD11B(+) cells is not required for susceptibility to experimental allergic encephalomyelitis.

Cellular immunology - 1 Jan 2000

Saligrama Naresha, Noubade Rajkumar, Case Laure K, Poynter Matthew E, Teuscher Cory

Abstract excerpt

The histamine H(1) receptor (Hrh1/H(1)R) was identified as an autoimmune disease gene in experimental allergic encephalomyelitis (EAE), the principal autoimmune model of multiple sclerosis (MS). Previously, we showed that selective re-expression of H(1)R by endothelial cells or T cells in H(1)RKO mice significantly reduced or complemented EAE severity and cytokine responses, respectively. H(1)R regulates innate...

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Identifiers

PMID: 23121973
DOI: 10.1016/j.cellimm.2012.06.012
PMCID: PMC3490133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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