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Article

IL-1 Receptor antagonist as a positional candidate gene in a murine model of allergic asthma.

Immunogenetics - 1 Oct 2006

Ramadas Ravisankar A, Li Xingnan, Shubitowski Dennis M, Samineni Sridhar, Wills-Karp Marsha, Ewart Susan L

Abstract excerpt

Interleukin-1 receptor antagonist (IL-1ra) is an inhibitor of the proinflammatory IL-1. The IL-1ra gene (Il1rn) maps near the allergen-induced bronchial hyper-responsiveness-1 locus, Abhr1, which we previously mapped to murine chromosome 2 using A/J (asthma susceptible) and C3H/HeJ (asthma resistant) mice. We evaluated the role of Il1rn in our mouse model by comparing its genomic sequence between A/J and C3H/HeJ...

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PMID: 17021861
DOI: 10.1007/s00251-006-0146-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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