Article
Autoimmune disease-associated histamine receptor H1 alleles exhibit differential protein trafficking and cell surface expression.
Journal of immunology (Baltimore, Md. : 1950) - 1 Jun 2008
Noubade Rajkumar, Saligrama Naresha, Spach Karen, Del Rio Roxana, Blankenhorn Elizabeth P, Kantidakis Theodoros, Milligan Graeme, Rincon Mercedes, Teuscher Cory
Abstract excerpt
Structural polymorphisms (L263P, M313V, and S331P) in the third intracellular loop of the murine histamine receptor H(1) (H(1)R) are candidates for Bphs, a shared autoimmune disease locus in experimental allergic encephalomyelitis and experimental allergic orchitis. The P-V-P haplotype is associa...
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