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Article

Genetics and epigenetics of autoimmune thyroid diseases: Translational implications.

Best practice & research. Clinical endocrinology & metabolism - 1 Mar 2023

Lee Hanna J, Stefan-Lifshitz Mihaela, Li Cheuk Wun, Tomer Yaron

Abstract excerpt

Hashimoto's thyroiditis (HT) and Graves' disease (GD) are prevalent autoimmune disorders, representing opposite ends of the clinical spectrum of autoimmune thyroid diseases (AITD). The pathogenesis involves a complex interplay between environment and genes. Specific susceptibility genes have been discovered that predispose to AITD, including thyroid-specific and immune-regulatory genes. Growing evidence has...

Topics

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Autoimmune Diseases
Diabetes and associated disorders
Epigenesis, Genetic
Genetic Predisposition to Disease
Graves Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Growth Hormone and Insulin-like Growth Factors

Hashimoto Disease

Thyroid Diseases

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Identifiers

PMID: 35459628
DOI: 10.1016/j.beem.2022.101661
PMCID: PMC9550878

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