Article
Genetic variation in TLR genes in Ugandan and South African populations and comparison with HapMap data.
PloS one - 1 Jan 2012
Baker Allison R, Qiu Feiyou, Randhawa April Kaur, Horne David J, Adams Mark D, Shey Muki, Barnholtz-Sloan Jill, Mayanja-Kizza Harriet, Kaplan Gilla, Hanekom Willem A, Boom W Henry, Hawn Thomas R, Stein Catherine M
Abstract excerpt
Genetic epidemiological studies of complex diseases often rely on data from the International HapMap Consortium for identification of single nucleotide polymorphisms (SNPs), particularly those that tag haplotypes. However, little is known about the relevance of the African populations used to collect HapMap data for study populations conducted elsewhere in Africa. Toll-like receptor (TLR) genes play a key role in...
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