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Article

Phenotypic and genetic barriers to establishment of horizontally transferred genes encoding ribosomal protection proteins.

The Journal of antimicrobial chemotherapy - 12 May 2021

Yadav Kavita, Garoff Linnéa, Huseby Douglas L, Hughes Diarmaid

Abstract excerpt

BACKGROUND: Ribosomal protection proteins (RPPs) interact with bacterial ribosomes to prevent inhibition of protein synthesis by tetracycline. RPP genes have evolved from a common ancestor into at least 12 distinct classes and spread by horizontal genetic transfer into a wide range of bacteria. Many bacterial genera host RPP genes from multiple classes but tet(M) is the predominant RPP gene found in Escherichia...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 33655294
DOI: 10.1093/jac/dkab056
PMCID: PMC8120329

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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