Article
Ribosomal RNAs are tolerant toward genetic insertions: evolutionary origin of the expansion segments.
Nucleic acids research - 1 Jun 2008
Yokoyama Takeshi, Suzuki Tsutomu
Abstract excerpt
Ribosomal RNAs (rRNAs), assisted by ribosomal proteins, form the basic structure of the ribosome, and play critical roles in protein synthesis. Compared to prokaryotic ribosomes, eukaryotic ribosomes contain elongated rRNAs with several expansion segments and larger numbers of ribosomal proteins. To investigate architectural evolution and functional capability of rRNAs, we employed a Tn5 transposon system to...
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