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Article

A six-nucleotide insertion-deletion polymorphism in the CASP8 promoter is associated with risk of coal workers' pneumoconiosis.

Journal of toxicology and environmental health. Part A - 1 Jan 2009

Ni Chunhui, Ye Yang, Wang Meilin, Qian Haiyang, Song Zhifang, Jia Xiaomin, Zhou Jianwei

Abstract excerpt

Coal workers' pneumoconiosis (CWP) is a chronic interstitial lung disease with a complex etiology that can occur after cumulative dust exposure. A case-control study was conducted to test the hypothesis that single-nucleotide polymorphisms (SNP) within CASPASE-8 (CASP8) promoter involved in resolution of inflammatory processes modulate the risk of CWP development. The study population consisted of 619 underground...

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Source

Identifiers

PMID: 19492233
DOI: 10.1080/15287390902841102

Genes

CASP8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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