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Article

Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation.

Journal of hepatology - 1 May 2013

Biggins Scott W, Trotter James, Gralla Jane, Burton James R, Bambha Kiran M, Dodge Jennifer, Brocato Megan, Cheng Linling, McQueen Matt, Forman Lisa, Chang Michael, Kam Igal, Everson Gregory, Spritz Richard A, Klintmalm Goran, Rosen Hugo R

Abstract excerpt

BACKGROUND & AIMS: IL28B single nucleotide polymorphisms are strongly associated with spontaneous HCV clearance and treatment response in non-transplant populations. A DDX58 single nucleotide polymorphism is associated with the antiviral response of innate lymphocytes. We aimed at evaluating the associations of donor and recipient IL28B (rs12979860 and rs8099917) and DDX58 (rs10813831) genotypes with severity of...

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Share to DEAD Box Protein 58
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Identifiers

PMID: 23333445
DOI: 10.1016/j.jhep.2012.12.027
PMCID: PMC3878646

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Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation.PMID 23333445Read ↗

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