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Interleukin-28B polymorphism in hepatitis C and liver transplantation.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 Jan 2013

Duarte-Rojo Andres, Deneke Matthew G, Charlton Michael R

Abstract excerpt

The discovery of interleukin-28B (IL-28B) single-nucleotide polymorphisms has opened an important new area of research in liver transplantation (LT) for hepatitis C virus (HCV). Both recipient- and donor-derived IL-28B genotypes affect the post-LT treatment response, with sustained virological response (SVR) rates oscillating from >50% in homozygotes for the favorable allele (up to 90% when this is present in...

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PMID: 23008132
DOI: 10.1002/lt.23554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interleukin-28B polymorphism in hepatitis C and liver transplantation.PMID 23008132Read ↗

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