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Article

Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes.

Development (Cambridge, England) - 1 Nov 2004

Zou Dan, Silvius Derek, Fritzsch Bernd, Xu Pin-Xian

Abstract excerpt

Eya1 encodes a transcriptional co-activator and is expressed in cranial sensory placodes. It interacts with and functions upstream of the homeobox gene Six1 during otic placodal development. Here, we have examined their role in cranial sensory neurogenesis. Our data show that the initial cell fate determination for the vestibuloacoustic neurons and their delamination appeared to be unaffected in the absence of...

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Identifiers

PMID: 15496442
DOI: 10.1242/dev.01437
PMCID: PMC3882150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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