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Article

Six family genes--structure and function as transcription factors and their roles in development.

BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Jul 2000

Kawakami K, Sato S, Ozaki H, Ikeda K

Abstract excerpt

The members of the Six gene family were identified as homologues of Drosophila sine oculis which is essential for compound-eye formation. The Six proteins are characterized by the Six domain and the Six-type homeodomain, both of which are essential for specific DNA binding and for cooperative interactions with Eya proteins. Mammals possess six Six genes which can be subdivided into three subclasses, and mutations...

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Identifiers

PMID: 10878574
DOI: 10.1002/1521-1878(200007)22:7<616::AID-BIES4>3.0.CO;2-R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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