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Article

The Eya1 phosphatase promotes Shh signaling during hindbrain development and oncogenesis.

Developmental cell - 6 Apr 2015

Eisner Adriana, Pazyra-Murphy Maria F, Durresi Ershela, Zhou Pengcheng, Zhao Xuesong, Chadwick Emily C, Xu Pin-Xian, Hillman R Tyler, Scott Matthew P, Greenberg Michael E, Segal Rosalind A

Abstract excerpt

Sonic hedgehog (Shh) signaling is critical in development and oncogenesis, but the mechanisms regulating this pathway remain unclear. Although protein phosphorylation clearly affects Shh signaling, little is known about phosphatases governing the pathway. Here, we conducted a small hairpin RNA (s...

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Identifiers

PMID: 25816987
DOI: 10.1016/j.devcel.2015.01.033
PMCID: PMC4418443

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25816987-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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