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Article

A lipid-dependent link between activity and oligomerization state of the M. tuberculosis SMR protein TBsmr.

Biochimica et biophysica acta - 1 Feb 2013

Mörs Karsten, Hellmich Ute A, Basting Daniel, Marchand Philipp, Wurm Jan Philip, Haase Winfried, Glaubitz Clemens

Abstract excerpt

TBsmr is a secondary active multidrug transporter from Mycobacterium tuberculosis that transports a plethora of compounds including antibiotics and fluorescent dyes. It belongs to the small multidrug resistance (SMR) superfamily and is structurally and functionally related to E. coli EmrE. Of particular importance is the link between protein function, oligomeric state and lipid composition. By freeze fracture EM,...

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PMID: 23103507
DOI: 10.1016/j.bbamem.2012.10.020

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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