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Article

Detecting and estimating contamination of human DNA samples in sequencing and array-based genotype data.

American journal of human genetics - 2 Nov 2012

Jun Goo, Flickinger Matthew, Hetrick Kurt N, Romm Jane M, Doheny Kimberly F, Abecasis Gonçalo R, Boehnke Michael, Kang Hyun Min

Abstract excerpt

DNA sample contamination is a serious problem in DNA sequencing studies and may result in systematic genotype misclassification and false positive associations. Although methods exist to detect and filter out cross-species contamination, few methods to detect within-species sample contamination are available. In this paper, we describe methods to identify within-species DNA sample contamination based on (1) a...

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PMID: 23103226
DOI: 10.1016/j.ajhg.2012.09.004
PMCID: PMC3487130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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