Article

The Human “Contaminome”: Bacterial, Viral, and Computational Contamination in Whole Genome Sequences from 1,000 Families

2022-02-02

Abstract excerpt

<h4>Background</h4> The unmapped readspace of whole genome sequencing data tends to be large but is often ignored. We posit that it contains valuable signals of both human infection and contamination. Using unmapped and poorly aligned reads from whole genome sequences (WGS) of over 1,000 families and 5,000 individuals, we present insights into common viral, bacterial, and computational contamination that plague w...

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Literature Corpus work: 83738504-b3e7-53e0-a946-e3aeb2f73e5c
DOI: 10.1101/2022.01.31.478554

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