Article
Exon 8-9 mutations of DNA polymerase β in ovarian carcinoma patients from Haldia, India.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Khanra Kalyani, Panda Kakali, Mitra A K, Sarkar Ranug, Bhattacharya Chandan, Bhattacharya Nandan
Abstract excerpt
BACKGROUND: Ovarian cancer is the number one killer among all the gynecological cancers. We undertook association study to identify potential alterations in the genomic DNA of a DNA repair gene, DNA polymerase beta (polβ), involved in base excision repair (BER), in ovarian carcinomas of patients from Haldia, India. Mutations, splice variants have been reported earlier in different tumors other than ovarian...
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