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Article

Association of a newly identified variant of DNA polymerase beta (polβΔ63-123, 208-304) with the risk factor of ovarian carcinoma in India.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012

Khanra Kalyani, Bhattacharya Chandan, Bhattacharyya Nandan

Abstract excerpt

BACKGROUND: DNA polymerase is a single-copy gene that is considered to be part of the DNA repair machinery in mammalian cells. The encoded enzyme is a key to the base excision repair (BER) pathway. It is evident that pol beta has mutations in various cancer samples, but little is known about ovarian cancer. AIM: Identification of any variant form of polβ cDNA in ovarian carcinoma and determination of association...

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Share to Adenocarcinoma, Clear Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA, Neoplasm

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Source

Identifiers

PMID: 22901161
DOI: 10.7314/apjcp.2012.13.5.1999

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