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Article

Whole-genome methylation analysis of benign and malignant colorectal tumours.

The Journal of pathology - 1 Apr 2013

Beggs Andrew D, Jones Angela, El-Bahrawy Mona, El-Bahwary Mona, Abulafi Muti, Hodgson Shirley V, Tomlinson Ian P M

Abstract excerpt

Changes in DNA methylation, whether hypo- or hypermethylation, have been shown to be associated with the progression of colorectal cancer. Methylation changes substantially in the progression from normal mucosa to adenoma and to carcinoma. This phenomenon has not been studied extensively and studies have been restricted to individual CpG islands, rather than taking a whole-genome approach. We aimed to study...

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PMID: 23096130
DOI: 10.1002/path.4132
PMCID: PMC3619233

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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