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Article

Temperature-dependence of the DnaA-DNA interaction and its effect on the autoregulation of dnaA expression.

The Biochemical journal - 15 Jan 2013

Saggioro Chiara, Olliver Anne, Sclavi Bianca

Abstract excerpt

The DnaA protein is a key factor for the regulation of the timing and synchrony of initiation of bacterial DNA replication. The transcription of the dnaA gene in Escherichia coli is regulated by two promoters, dnaAP1 and dnaAP2. The region between these two promoters contains several DnaA-binding sites that have been shown to play an important role in the negative auto-regulation of dnaA expression. The results...

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Source

Identifiers

PMID: 23092251
DOI: 10.1042/BJ20120876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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