Article
Role of DNA methylation at GATC sites in the dnaA promoter, dnaAp2.
Journal of molecular microbiology and biotechnology - 1 Jul 2000
Kedar G C, Ozcan F, Guzmán E C, Smith D W, Newman V G, Zyskind J W
Abstract excerpt
DnaA protein is required for the initiation of DNA replication at the bacterial chromosomal origin, oriC, and at the origins of many plasmids. The concentration of DnaA protein is an important factor in determining when initiation occurs during the cell cycle. Methylation of GATC sites in the dnaAp2 promoter, two of which are in the -35 and -10 sequences, has been predicted to play an important role in regulating...
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