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Article

Clearance of genetic variants of amyloid β peptide by neuronal and non-neuronal cells.

Protein and peptide letters - 1 May 2013

Panchal Maï, El Abida Boutaïna, Lazar Noureddine, Fahy Christine, Dubost Lionel, Friguet Bertrand, Rholam Mohamed

Abstract excerpt

The presence of senile plaques in the brain is one of the pathological hallmarks of Alzheimer's disease (AD). The biogenesis and clearance of the amyloid β peptide (A β ), the main component of the lesions, lie at the center of the pathogenesis of AD. In sporadic AD, the increase of A β levels seems to be indicative of failure of clearance mechanisms. We previously showed that the clearance of the wild type A β40...

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PMID: 23092134
DOI: 10.2174/0929866511320050008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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