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Article

Mechanisms of Abeta clearance and catabolism.

Neuromolecular medicine - 1 Jan 2003

Guénette Suzanne Y

Abstract excerpt

Mutations that result in an increased generation of amyloid beta peptide (Abeta) account for less than 5% of Alzheimer's disease (AD). Data suggesting that late onset AD risk factors play a role in Abeta turnover in the brain have shifted some of the research focus to the study of Abeta clearance and degradation and the impact of these processes on the etiology of Alzheimer's disease (AD). This review will...

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PMID: 14716023
DOI: 10.1385/NMM:4:3:147

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