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Article

Integrative analysis of somatic mutations altering microRNA targeting in cancer genomes.

PloS one - 1 Jan 2012

Ziebarth Jesse D, Bhattacharya Anindya, Cui Yan

Abstract excerpt

Determining the functional impact of somatic mutations is crucial to understanding tumorigenesis and metastasis. Recent sequences of several cancers have provided comprehensive lists of somatic mutations across entire genomes, enabling investigation of the functional impact of somatic mutations in non-coding regions. Here, we study somatic mutations in 3'UTRs of genes that have been identified in four cancers and...

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Share to 3' Untranslated Regions
Share to Cell Transformation, Neoplastic
Share to Germ-Line Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasm Metastasis

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Source

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Identifiers

PMID: 23091610
DOI: 10.1371/journal.pone.0047137
PMCID: PMC3473044

Genes

EPHA3
GSDMA
KLK3
MITF
SCG3
SPRY4
TAL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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