Article
Correlation between interleukin‑23 receptor gene polymorphisms and risk of hepatitis B virus infection in patients.
Molecular medicine reports - 1 Aug 2013
Peng Qiliu, Qin Yanping, Chen Zhiping, Deng Yan, Xu Juanjuan, Li Shan, Qin Xue
Abstract excerpt
There is an increasing amount of evidence supporting the hypothesis that the pathological stage from hepatitis to hepatocellular carcinoma (HCC) is a chronic inflammatory process. Interleukin‑23 (IL‑23) is an important mediator and modulator of inflammation. Specific polymorphisms in the genes encoding subunits of the IL‑23 receptor (IL‑23R) have been consistently observed to be associated with chronic...
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