Article
Gene-centric genomewide association study via entropy.
Genetics - 1 May 2008
Cui Yuehua, Kang Guolian, Sun Kelian, Qian Minping, Romero Roberto, Fu Wenjiang
Abstract excerpt
Genes are the functional units in most organisms. Compared to genetic variants located outside genes, genic variants are more likely to affect disease risk. The development of the human HapMap project provides an unprecedented opportunity for genetic association studies at the genomewide level for elucidating disease etiology. Currently, most association studies at the single-nucleotide polymorphism (SNP) or the...
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