Article
MDR1 polymorphisms associated with risk and survival in diffuse large B-cell lymphoma.
Leukemia & lymphoma - 1 Jun 2013
Hu Li-Li, Yu Bingyun, Yang Jine
Abstract excerpt
MDR1 encodes an adenosine triphosphate (ATP)-dependent efflux transporter that protects the body from environmental xenobiotics to maintain optimal health. Five single nucleotide polymorphisms (SNPs) of MDR1, T-2410C, T-129C, C1236T, G2677T/A and C3435T, were identified in our previous study. To investigate further the biological significance of these SNPs, we genotyped the SNPs in 135 patients with diffuse large...
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