Article
MDR1 polymorphisms have an impact on the prognosis of Chinese diffuse large B cell lymphoma patients.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2016
Ni Ying, Yin Guangli, Xiao Zhengrui, Fan Lei, Wang Li, Wu Yujie, Wu Hanxin, Qian Sixuan, Xu Wei, Li Jianyong, Miao Kourong, Qiu Hairong
Abstract excerpt
MDR1 (multidrug resistance 1) encodes an adenosine triphosphate (ATP)-dependent efflux transporter that plays a fundamental role in transportation of harmful compounds outside cells to maintain optimal health. The present study was aimed to investigate whether the MDR1 gene single nucleotide polymorphisms (SNPs) were associated with the prognosis of diffuse large B cell lymphoma (DLBCL). Three common SNPs,...
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