Article
The Impact of Drug Metabolism Gene Polymorphisms on Therapeutic Response and Survival in Diffuse Large B-Cell Lymphoma Patients.
The Israel Medical Association journal : IMAJ - 1 Apr 2018
Pál Ildikó, Illés Árpád, Gergely Lajos, Pál Tibor, Radnay Zita, Szekanecz Zoltán, Zilahi Erika, Váróczy László
Abstract excerpt
BACKGROUND: Diffuse large B-cell lymphoma (DLBCL) accounts for 30% of all non-Hodgkin lymphomas (NHL) and 80% of agressive lymphomas. Besides the traditional International Prognostic Index (IPI), some other factors may also influence the prognosis of DLBCL patients. OBJECTIVES: To study how the genetic polymorphisms in the metabolic pathway influence the event-free and overall survivals and therapeutic responses...
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