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Article

CARD8 rs2043211 (p.C10X) polymorphism is not associated with disease susceptibility or cardiovascular events in Spanish rheumatoid arthritis patients.

DNA and cell biology - 1 Jan 2013

García-Bermúdez Mercedes, López-Mejías Raquel, González-Juanatey Carlos, Corrales Alfonso, Castañeda Santos, Ortiz Ana M, Miranda-Filloy José A, Gómez-Vaquero Carmen, Fernández-Gutiérrez Benjamín, Balsa Alejandro, Pascual-Salcedo Dora, Blanco Ricardo, Llorca Javier, Martín Javier, González-Gay Miguel A

Abstract excerpt

Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis, which is the main cause of increased cardiovascular (CV) morbidity and mortality in RA patients. CARD8 is a constituent of inflammasome, which regulates interleukin 1-beta production, and has been associated with a worse disease course in early RA. One thousand six hundred twenty-one patients...

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Identifiers

PMID: 23088220
DOI: 10.1089/dna.2012.1836
PMCID: PMC3530932

Genes

CARD8
ACR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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