Article
Lack of common NOD2 variants in Japanese patients with Crohn's disease.
Gastroenterology - 1 Jul 2002
Inoue Nagamu, Tamura Kazuo, Kinouchi Yoshitaka, Fukuda Yoshihiro, Takahashi Seiichi, Ogura Yasunori, Inohara Naohiro, Núñez Gabriel, Kishi Yusuke, Koike Yuji, Shimosegawa Tooru, Shimoyama Takashi, Hibi Toshifumi
Abstract excerpt
BACKGROUND & AIMS: Previous studies have linked Crohn's disease (CD) to the pericentromeric region of chromosome 16 (IBD1). Three independent studies of Western populations have recently shown that 3 variants of NOD2, a gene located at 16q12, are associated with susceptibility to CD. Here, we have evaluated the 3 NOD2 variants in Japanese patients to determine whether the gene is also associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.