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Article

Feasibility of an early Alzheimer's disease immunosignature diagnostic test.

Journal of neuroimmunology - 15 Jan 2013

Restrepo Lucas, Stafford Phillip, Johnston Stephen Albert

Abstract excerpt

A practical diagnostic test is needed for early Alzheimer's disease (AD) detection. Immunosignaturing, a technology that employs antibody binding to a random-sequence peptide microarray, generates profiles that distinguish transgenic mice engineered with familial AD mutations (APPswe/PSEN1-dE9) from non-transgenic littermates. It can also detect an AD-like signature in humans. Here, we assess the changes in the...

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Source

Identifiers

PMID: 23084373
DOI: 10.1016/j.jneuroim.2012.09.014

Genes

PSEN1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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