Article
Reverse engineering of Alzheimer's disease based on biomarker pathways analysis.
Neurobiology of aging - 1 Sept 2014
Richens Joanna L, Morgan Kevin, O'Shea Paul
Abstract excerpt
Alzheimer's disease (AD) poses an increasingly profound problem to society, yet progress toward a genuine understanding of the disease remains worryingly slow. Perhaps, the most outstanding problem with the biology of AD is the question of its mechanistic origins, that is, it remains unclear wherein the molecular failures occur that underlie the disease. We demonstrate how molecular biomarkers could help define...
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