Article
Microreview: Type IV secretion in the obligatory intracellular bacterium Anaplasma phagocytophilum
28 Jul 2010
Abstract excerpt
Anaplasma phagocytophilum is an obligatory intracellular bacterium that infects neutrophils, the primary host defence cells. Consequent effects of infection on host cells result in a potentially fatal systemic disease called human granulocytic anaplasmosis. Despite ongoing reductive genome evolution and deletion of most genes for intermediary metabolism and amino acid biosynthesis, Anaplasma has also experienced...
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