Article

Translocation of YopJ family effector proteins through the VirB/VirD4 T4SS of <i>Bartonella</i>

2024-03-24

Abstract excerpt

The evolutionary conserved YopJ family comprises numerous type-III-secretion system (T3SS) effectors of diverse mammalian and plant pathogens that acetylate host proteins to dampen immune responses. Acetylation is mediated by a central acetyltransferase domain that is flanked by conserved regulatory sequences, while a non-conserved N-terminal extension encodes the T3SS-specific translocation signal. Bartonella sp...

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Literature Corpus work: dd7b0135-aae6-527b-b351-81fdbadd8c3c
DOI: 10.1101/2024.03.23.586424

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