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Article

Rational substrate and enzyme engineering of transketolase for aromatics.

Organic & biomolecular chemistry - 7 Dec 2012

Payongsri Panwajee, Steadman David, Strafford John, MacMurray Andrew, Hailes Helen C, Dalby Paul A

Abstract excerpt

The uses of 3-formylbenzoic acid and 4-formylbenzoic acid as molecular probes along with previous and new transketolase mutants revealed the factors governing the rate of reaction between transketolase and aromatic aldehydes. The novel α,α-dihydroxyketones were produced at 15 to 30-fold higher yi...

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PMID: 23079923
DOI: 10.1039/c2ob25751c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23079923-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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