Article

A Hybrid Type I and II Polyketide Synthases Yields Distinct Aromatic Polyketides

2024-08-29

Abstract excerpt

<h4>ABSTRACT</h4> Bacterial aromatic polyketides are compounds with multiple aromatic rings synthesized by bacterial type II polyketide synthases (PKSs), some of which have been developed into clinical drugs. Compounds containing aromatic polyketides synthesized by a hybrid type I and type II PKSs are extremely rare. Here, we report the discovery of a gene cluster encoding both modular type I PKS, type II PKS and...

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Literature Corpus work: 85c296ab-48b1-5296-a8ad-a1a2a7cafeb4
DOI: 10.1101/2024.08.28.610196

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