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Article

Histotype-specific copy-number alterations in ovarian cancer.

BMC medical genomics - 18 Oct 2012

Huang Ruby Yunju, Chen Geng Bo, Matsumura Noriomi, Lai Hung-Cheng, Mori Seiichi, Li Jingjing, Wong Meng Kang, Konishi Ikuo, Thiery Jean-Paul, Goh Liang

Abstract excerpt

BACKGROUND: Epithelial ovarian cancer is characterized by multiple genomic alterations; most are passenger alterations which do not confer tumor growth. Like many cancers, it is a heterogeneous disease and can be broadly categorized into 4 main histotypes of clear cell, endometrioid, mucinous, and serous. To date, histotype-specific copy number alterations have been difficult to elucidate. The difficulty lies in...

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Topics

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Share to Adenocarcinoma, Mucinous
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystadenocarcinoma, Serous

Share to DNA Copy Number Variations

Share to Ovarian Neoplasms

Share to ras Proteins

Share to Receptor, ErbB-2

Share to Tropomyosin

Source

Open in PubMed Open full text

Identifiers

PMID: 23078675
DOI: 10.1186/1755-8794-5-47
PMCID: PMC3567940

Genes

ERBB2
KRAS
TPM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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