Article
Homeobox genes in the rodent pineal gland: roles in development and phenotype maintenance.
Neurochemical research - 1 Jun 2013
Rath Martin F, Rohde Kristian, Klein David C, Møller Morten
Abstract excerpt
The pineal gland is a neuroendocrine gland responsible for nocturnal synthesis of melatonin. During early development of the rodent pineal gland from the roof of the diencephalon, homeobox genes of the orthodenticle homeobox (Otx)- and paired box (Pax)-families are expressed and are essential for normal pineal development consistent with the well-established role that homeobox genes play in developmental...
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