Article
Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.
Development (Cambridge, England) - 1 Mar 2004
Wang Song S, Lewcock Joseph W, Feinstein Paul, Mombaerts Peter, Reed Randall R
Abstract excerpt
The mammalian Olf1/EBF (O/E) family of repeated helix-loop-helix (rHLH) transcription factors has been implicated in olfactory system gene regulation, nervous system development and B-cell differentiation. Ebf (O/E1) mutant animals showed defects in B-cell lineage and brain regions where it is the only O/E family member expressed, but the olfactory epithelium appeared unaffected and olfactory marker expression...
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