Article

Usherin in the pineal gland: altered sleep in zebrafish models of Usher syndrome type 2a

2026-03-11

Abstract excerpt

<h4>ABSTRACT</h4> Usher syndrome type 2A (USH2a), the most common form of hereditary deaf-blindness, is frequently accompanied by fatigue and poor sleep quality. As these sleep problems occur independently of visual decline, it is hypothesized that the USH2A -encoded protein usherin regulates sleep and circadian rhythmicity via an extra-retinal mechanism. Ush2a knockout zebrafish models were utilized to investi...

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Literature Corpus work: 59021715-e78e-5f28-8721-d7505104a033
DOI: 10.64898/2026.03.09.710525

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