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Article

Rodent Aanat: intronic E-box sequences control tissue specificity but not rhythmic expression in the pineal gland.

Molecular and cellular endocrinology - 30 May 2007

Humphries Ann, Wells Tim, Baler Ruben, Klein David C, Carter David A

Abstract excerpt

Arylalkylamine N-acetyltransferase (Aanat) is the penultimate enzyme in the serotonin-N-acetylserotonin-melatonin pathway. It is nearly exclusively expressed in the pineal gland and the retina. A marked rhythm of Aanat gene expression in the rat pineal is mediated by cyclic AMP response elements located in the promoter and first intron. Intron 1 also contains E-box elements, which mediate circadian gene...

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Identifiers

PMID: 17363136
DOI: 10.1016/j.mce.2007.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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