Article
The association between small vessel infarcts and the activities of amyloid-β peptide degrading proteases in apolipoprotein E4 allele carriers.
Angiology - 1 Nov 2013
Zhu Haihao, Bhadelia Rafeeque A, Liu Zhiheng, Vu Linh, Li Huajie, Scott Tammy, Bergethon Peter, Mwamburi Mkaya, Rosenzweig James L, Rosenberg Irwine, Qiu Wei Qiao
Abstract excerpt
Small vessel (SV) and large vessel (LV) brain infarcts are distinct pathologies. Using a homebound elderly sample, the numbers of either infarct subtypes were similar between those apolipoprotein E4 allele (ApoE4) carriers (n = 80) and noncarriers (n = 243). We found that the higher the number of SV infarcts, but not LV infarcts, a participant had, the higher the activity of substrate V degradation in serum...
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