Article
Angiotensin converting enzyme inhibitors and the reduced risk of Alzheimer's disease in the absence of apolipoprotein E4 allele.
Journal of Alzheimer's disease : JAD - 1 Jan 2013
Qiu Wei Qiao, Mwamburi Mkaya, Besser Lilah M, Zhu Haihao, Li Huajie, Wallack Max, Phillips Leslie, Qiao Liyan, Budson Andrew E, Stern Robert, Kowall Neil
Abstract excerpt
Our cross-sectional study showed that the interaction between apolipoprotein E4 (ApoE4) and angiotensin converting enzyme (ACE) inhibitors was associated with Alzheimer's disease (AD). The aim of this longitudinal study was to differentiate whether ACE inhibitors accelerate or reduce the risk of AD in the context of ApoE alleles. Using the longitudinal data from the National Alzheimer's Coordinating Center (NACC)...
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