Article
Association of ADAM33 gene polymorphisms with adult-onset asthma and its severity in an Indian adult population.
Journal of genetics - 1 Aug 2011
Tripathi Priya, Awasthi Shally, Prasad Rajendra, Husain Nuzhat, Ganesh Subramaniam
Abstract excerpt
ADAM33, a member of the ADAM (a disintegrin and metalloprotease) gene family, is an asthma susceptibility gene originally identified by positional cloning. In the present study, we investigated the possible association of five single-nucleotide polymorphisms (SNPs) in the ADAM33 (rs511898, rs528557, rs44707, rs597980 and rs2787094) with adult-onset asthma in an Indian population. The study included 175 patients...